Pseudomonas aeruginosa is becoming one of the more important cause of gram-negative infections healthcare-associated and increasingly resistant to multiple antibiotics.

It is the most common, opportunistic and hard to eradicate pathogen isolated from patients who have been hospitalized longer than one week, and it is a frequent cause of nosocomial infections. Pseudomonas infections are complicated and can be life-threatening.


Gramnegative bacteria are enclosed in a protective capsule, preventing white blood cells (which fight infections) from ingesting the bacteria. Beneath the protecting capsule is an outer membrane that prevents against antibiotics, such as penicillin to be effective. If altered, the membrane can release endotoxins (toxic substances), that will contribute to worsen symptoms during the infections like:
Pneumonia, Peritonitis, Brucellosis, Campylobacter infections, Cholera, Escherichia coli infections, Whooping cough, Salmonella, Typhoid fever, Shigellosis, Tularemia and of course Pseudomonas infections.

Unfortunately, Gram-negative bacteria are increasing their resistance to antibiotics. This may depend on the mutation of their genes: in some cases, a bacterium can “take” the antibiotic resistance gene of another bacterium and make it its own.

It is a spore-forming bacterium: this means that, under conditions of poor nutrition and unfavorable environment, it is capable of producing spores, a particular cell characterized by a cover that makes it resistant even to large variations in temperature and disinfectants.


Pseudomonas aeruginosa infections range from minor external infections to severe and life-threatening. These infections occur more frequently and tend to be more severe in those who are debilitated by certain serious illnesses; diabetes or cystic fibrosis; compromised immune system, (HIV); and those who take medications that suppress the immune system.

The danger of these bacteria also derives from the fact that they can infect the entire human body: epithelial system, bone system, ears, eyes, urinary tract, lungs, heart valves, wounds (such as burns, injuries or surgical wounds).

The use of medical devices, such as mechanical ventilators, intubation cannulas, and catheters inserted into the bladder or vein, increases the risk of infection with this bacterium.

Generally, Pseudomonas aeruginosa infections must be treated with a carefully chosen combination of antimicrobial drugs and specific antibiotics. In some instances the removal of necrotic tissue or the drainage of abscesses is necessary. Amputation is only done in extreme cases.


MEDISYSTEM combines automated dispensing Class I (CE marked / FDA registered) medical devices (micro-nebulizers with 1 to 4 nozzles) and AMIL Care ready-to-use Eco-friendly chemical solutions. The system provides a high-level disinfection with “NO TOUCH” technology able to treat volumes ranging from 10 to 10,000 m3 (350 to 350,000 ft3).

Our Medibios devices are available in different configurations. In particular, Medibios Plus and Medibios Plus Hub are tailored to meet the needs of the medical industry. Its advanced functions allow full traceability of treatment results.

The system disinfects by saturation of the most confined and difficult to reach areas, also is effective on smooth and porous surfaces.  Through a turbine, particles of (<1 to 5 µm) are emitted in constant quantity according to the established assigned protocol, complying with current safety and health regulations.

Medisystem’s spectrum of effectiveness is higher than most competitive systems, since it boasts virucidal, bactericidal, mycobactericidal, fungicidal and sporicidal activity. Standardization, traceability and automation of the process allows greater safety and excludes the possibility of human error because it can be used regardless of operator intervention.

The effectiveness of the production process is certified at all stages. This is the best guarantee that the product always meets the most stringent standards like electromagnetic compatibility and electrical safety. The result is simple (not corrosive/no residue), safe and with documented efficacy against multi-resistant pathogens.