{"id":8267,"date":"2023-06-30T16:52:15","date_gmt":"2023-06-30T14:52:15","guid":{"rendered":"https:\/\/www.amil-care.com\/2023\/06\/30\/antibiotico-resistenza\/"},"modified":"2023-08-02T13:13:04","modified_gmt":"2023-08-02T11:13:04","slug":"antibiotic-resistance","status":"publish","type":"post","link":"https:\/\/www.amil-care.com\/en\/2023\/06\/30\/antibiotic-resistance\/","title":{"rendered":"Antibiotic resistance: what is it?"},"content":{"rendered":"<p><span data-contrast=\"none\">As the world continues its efforts against the Sars-CoV-2 virus, one cannot forget &#8220;superbugs,&#8221; that is, <\/span>bacteria that resist the action of antibiotics. It is enough to mention that these caused the direct deaths of 1.27 million people in 2019 alone.<\/p>\n<p>This number may not be particularly worrying, but if we think of the estimates that AIDS and malaria caused in 2019 &#8211; respectively 860,000 and 640,000 deaths &#8211; the perception changes, and not a little.<\/p>\n<p>The confirmation came thanks to a report published in the scientific journal The Lancet: the careful and timely analysis, entitled &#8220;Global Research on Antimicrobial Resistance&#8221;, also calculated that antibiotic-resistant infections played an important role in almost 5 million of deaths. The scientists&#8217; work covered 204 countries around the world and confirmed that antibiotic resistance (AMR) poses a real threat to the health of all, especially in low- and middle-income countries.<\/p>\n<p><span data-contrast=\"none\">We at <\/span><b><span data-contrast=\"none\">AMIL Care<\/span><\/b><span data-contrast=\"none\"> believe it is essential to reflect on this issue. For this reason, we decided to dedicate an article intended to assist the work of professionals such as purchasing managers in hospitals, medical equipment managers, clinical engineers (Aiic), safety and hygiene managers (HSE), and clinical risk managers (i.e., risk managers).<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2>Antibiotic resistance: a definition<\/h2>\n<p><span data-contrast=\"none\">When we talk about <\/span><b><span data-contrast=\"none\">antibiotic resistance,<\/span><\/b><span data-contrast=\"none\"> we mean &#8220;the ability of a bacterium to resist the action of one or more antibiotic drugs&#8221; and to survive and multiply even in their presence.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">Antibiotic resistance<\/span><\/b><span data-contrast=\"none\">, at least in part, is a phenomenon that can be natural \u2013 when the bacterium is naturally resistant to an antibiotic -, but also acquired \u2013 when the bacterium adapts to resist an antibiotic through modifications to its genetic heritage.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">Antibiotic resistance<\/span><\/b> <span data-contrast=\"none\">may therefore depend on (and increase) due to human actions.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2>The Impact of antibiotic resistance in Italy<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2>\n<p><span data-contrast=\"none\">In Italy, <\/span><b><span data-contrast=\"none\">the surveillance of antibiotic resistance<\/span><\/b><span data-contrast=\"none\"> is coordinated by the Higher Institute of Health and is based on a network of hospital laboratories that send antibiotic sensitivity data for pathogens isolated from invasive infections.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">There are 8 pathogens under surveillance.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">Among Gram-positive bacteria:<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li><b> <\/b><i><span data-contrast=\"none\">Staphylococcus aureus,<\/span><\/i><\/li>\n<li><b><i> <\/i><\/b><i><span data-contrast=\"none\">Streptococcus pneumonia,<\/span><\/i><\/li>\n<li><b><i><\/i><\/b><i><span data-contrast=\"none\"> Enterococcus faecalis and Enterococcus faecium<\/span><\/i><span data-contrast=\"none\">.<\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"none\">Among the Gram-negative bacteria:<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li><b><\/b> <i><span data-contrast=\"none\">Escherichia coli,<\/span><\/i><\/li>\n<li><b><i><\/i><\/b><i><span data-contrast=\"none\"> Klebsiella pneumoniae,<\/span><\/i><\/li>\n<li><b><i> <\/i><\/b><i><span data-contrast=\"none\">Pseudomonas aeruginosa,<\/span><\/i><\/li>\n<li><b><i> <\/i><\/b><i><span data-contrast=\"none\">Acinetobacter species.<\/span><\/i><\/li>\n<\/ul>\n<h2>\u00a0What causes antibiotic resistance?<\/h2>\n<p><span data-contrast=\"none\">There are many possible causes of <\/span><b><span data-contrast=\"none\">antibiotic resistance<\/span><\/b><span data-contrast=\"none\">. Let&#8217;s look at some of them briefly.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li><b> <\/b><span data-contrast=\"none\">The excessive or inappropriate prescription of antibiotic drugs, both in medicine and in veterinary medicine;<\/span><\/li>\n<li><b><\/b><span data-contrast=\"none\"> the inappropriate use and, in general, the excessive use of antibiotic drugs;<\/span><\/li>\n<li><b> <\/b><span data-contrast=\"none\">incorrect use of medicines by patients;<\/span><\/li>\n<li><b> <\/b><span data-contrast=\"none\">the use of antibiotics in zootechnics and agriculture;<\/span><\/li>\n<li><b><\/b><span data-contrast=\"none\"> the prevalence of hospital-acquired infections caused by antibiotic-resistant microorganisms, and the resulting limited control of these infections;<\/span><\/li>\n<li><b><\/b><span data-contrast=\"none\"> an increased diffusion of resistant strains, often due to an increase in international travel and migratory flows.<\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"none\">In particular, the continuous use of antibiotics favors the emergence, multiplication, and spread of resistant strains. Not only that: the presence of <\/span><b><span data-contrast=\"none\">pathogens resistant to multiple antibiotics <\/span><\/b><span data-contrast=\"none\">(in these <\/span><span data-contrast=\"none\">cases,<\/span><span data-contrast=\"none\"> we speak of <\/span><i><span data-contrast=\"none\">multidrug resistance<\/span><\/i><span data-contrast=\"none\">) further reduces the possibility of an effective treatment.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">In addition, it should not be forgotten that this phenomenon largely concerns healthcare-related infections, which then arise and spread within hospitals and similar healthcare facilities.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2>Antibiotic resistance: the consequences<\/h2>\n<p><span data-contrast=\"none\">The spread and multiplication of <\/span><b><span data-contrast=\"none\">antibiotic-resistant bacteria<\/span><\/b><span data-contrast=\"none\"> in hospitals or healthcare facilities is a problem that should not be underestimated, as the infections caused by them can be not only serious but also difficult to cure.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">All over the world, <\/span><b><span data-contrast=\"none\">antibiotic resistance<\/span><\/b><span data-contrast=\"none\"> increases the number of cases of illness and death and prolongs the duration of hospitalizations. In Italy, the percentage of bacteria resistant to antibiotics and causing infections can fluctuate between 30 and 60%. The greatest risk is that, over time, pan-resistant bacteria, i.e. resistant to all antibiotics, may develop.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Without antibiotics, it is worth specifying that various treatments would no longer be possible, starting from organ transplants to chemotherapy, intensive care, and many other procedures.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><i><span data-contrast=\"none\">Since 2001, AR-ISS surveillance has been active in Italy, coordinated by the Higher Institute of Health, for the collection of data relating to the spread of antimicrobial resistance in healthcare facilities. Starting in 2017, a <\/span><\/i><i><span data-contrast=\"none\">Plan to combat AMR <\/span><\/i><i><span data-contrast=\"none\">was approved in Italy, which concerns, in addition to those antibiotics, also resistance to antifungal, antiprotozoal, and antiviral drugs.<\/span><\/i><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2>Antibiotic resistance: prevention and protection<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2>\n<p><span data-contrast=\"none\">Many studies show that hundreds of thousands of deaths are caused by common and previously treatable infections, such as those of the respiratory tract or blood, because the bacteria that cause them have become resistant to treatments over time.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">There are several ways a country can tackle the phenomenon of <\/span><b><span data-contrast=\"none\">antibiotic resistance:<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li><b><span data-contrast=\"none\">rapid and substantial investment in new treatments;<\/span><\/b><\/li>\n<li><b><span data-contrast=\"none\"> an improvement in the efficiency of infection control measures;<\/span><\/b><\/li>\n<li><b><span data-contrast=\"none\"> optimization of the use of antibiotics.<\/span><\/b><\/li>\n<\/ul>\n<h2>AMIL Care devices in response to antibiotic resistance<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/h2>\n<p><span data-contrast=\"none\">How to prevent <\/span><b><span data-contrast=\"none\">antibiotic resistance<\/span><\/b><span data-contrast=\"none\">, and how to fight it?\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">First of all, it is good to sanitize hospital environments correctly, using the right tools and relying on those who hold the most effective patents.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">It is now established that contamination of surfaces around the ward plays an important role in the transmission of microorganisms, starting with <\/span><i><span data-contrast=\"none\">Staphylococcus<\/span><\/i> <i><span data-contrast=\"none\">aureus<\/span><\/i><span data-contrast=\"none\"> (MRSA), Vancomycin-resistant <\/span><i><span data-contrast=\"none\">Enterococci<\/span><\/i><span data-contrast=\"none\"> (VRE), <\/span><i><span data-contrast=\"none\">Clostridium difficile<\/span><\/i><span data-contrast=\"none\">, <\/span><i><span data-contrast=\"none\">Acinetobacter baumanii, Norovirus, and Klebsiella pneumonia.<\/span><\/i><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">AMIL Care<\/span><\/b><span data-contrast=\"none\"> offers an effective, simple, and safe system, based on a patented and certified device.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">We are talking about the <\/span><a href=\"https:\/\/www.amil-care.com\/en\/medical\/products\/devices\/\" target=\"_blank\" rel=\"noopener\"><b><span data-contrast=\"none\">Medisystem<\/span><\/b><\/a> <span data-contrast=\"none\">system and in particular the <\/span><b><span data-contrast=\"none\">Medibios Plus<\/span><\/b><span data-contrast=\"none\"> device, the latest generation micro-nebulizer of ready-to-use solutions.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.amil-care.com\/en\/medical\/products\/devices\/\" target=\"_blank\" rel=\"noopener\"><b><span data-contrast=\"none\">Medibios Plus<\/span><\/b><\/a><span data-contrast=\"none\"> is a practical, handy, and technological class I medical device CE marked, and is designed to be used in various hospital areas. It is positioned in the intermediate range of the <\/span><b><span data-contrast=\"none\">Medibios range produced by AMIL Care<\/span><\/b><span data-contrast=\"none\"> and is covered by a European, American, and Mexican patent.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">Medibios Plus<\/span><\/b> <span data-contrast=\"none\">supplies liquid solutions such as <\/span><b><span data-contrast=\"none\">class IIa medical devices, biocides, medical-surgical aids and supplies, and sanitizers<\/span><\/b><span data-contrast=\"none\">.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Each operator must scrupulously comply with the warnings and instructions provided in the manual, contained within each product.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>As the world continues its efforts against the Sars-CoV-2 virus, one cannot forget &#8220;superbugs,&#8221; that is, bacteria that resist the action of antibiotics. It is enough to mention that these caused the direct deaths of 1.27 million people in 2019 alone. This number may not be particularly worrying, but if we think of the estimates [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8165,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[65],"tags":[],"class_list":["post-8267","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-sector"],"acf":[],"yoast_head":"<title>What is meant by antibiotic resistance and the answers to the problem<\/title>\n<meta name=\"description\" content=\"Let&#039;s find out what antibiotic resistance is and what are the answers to the increasingly worrying problem of antibiotic-resistant bacteria.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.amil-care.com\/en\/2023\/06\/30\/antibiotic-resistance\/\" \/>\n<meta property=\"og:locale\" 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